Immune Response Template | Annotation and numerical description of immune response in humans
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Immune Response Template

Annotation and numerical description of immune response in humans

Immune Response Template

IRT is a project aimed to collect, analyze and visualize available data on immune cells, cytokine, chemokines and other mediators interactions in humans. The unique feature of the project is its focus on quantitative systems pharmacology (QSP) modeling. The goal of the project is a tool for investigation of immune system and its multiple interactions, and for development of QSP models/platforms related to immune in human.

IRT team makes efforts in two directions: the development of database on human immune cells interaction (IRT database) and the development of tools for navigation and model creation (IRT navigator).

IRT database

Current release IRT database 1.0 describes about 10 types of cells, 10 surface molecules, 20 cytokines and 300 processes in 3 compartments: blood/plasma, lymph nodes and unspecified tissue.

IRT database includes:

immune cell passport immune cell passport

cytokines sources profile cytokines sources profile

The database is distributed under two revisions:

try demo online request for full version
The demo version and code is available online for free under CC BY-ND 4.0 lisence. The full version can be obtained under commercial license after request to irt@insysbio.com

IRT navigator

IRT navigator provides the intuitive interface for searching the information and model template creation. IRT navigator functionality:

IRT navigator IRT navigator

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